Curriculum Vitae

OHSU, Knight Cancer Institute, Bioinformatics Group

• Postdoctoral Researcher, July 2011 - April 2015

MAMM Magazine

• Assistant Editor, March 2005 - July 2006
• MAMM is a magazine devoted to the needs of women with breast and gynecological cancers, their families and healthcare providers

UCLA, Department of Medicine, Nephrology Division

• Staff Research Associate, May 2002 - August 2003
• Volunteer Research Assistant, July 2000 - June 2001
• I conducted gene mapping experiments to locate the mutated gene responsible for cystic kidneys in the pcy mouse model of polycystic kidney disease.

Relsys International, Inc.

• Software QA Engineer, summers of 1997 and 1998
• I designed and conducted software validation protocols for a major developer of pharmaceutical adverse reaction management software.

Teaching

• Bioinformatics Programming & Scripting, Instructor, fall 2012 - present
• Databases, guest lecturer, winter 2014 - present
• Bioinformatics & Computational Biology: Algorithms, co-taught with Drs. Shannon McWeeney and David Maier, fall 2009
• Medical Decision Making, co-taught with Dr. Karen Eden, winter 2010

Publications

• Publication list on Google Scholar
• Mooney MA, McWeeney SK, Faraone S, Hinney A, Hebebrand J; IMAGE2 Consortium; German ADHD GWAS Group, Nigg JT, Wilmot B. Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. Am J Med Genet B Neuropsychiatr Genet. 2016 Mar 22. doi: 10.1002/ajmg.b.32446. PMID: 27004716 [Impact Factor: 3.4]
• Mooney MA, Wilmot B. Gene set analysis: A step-by-step guide. Am J Med Genet B Neuropsychiatr Genet. 2015 Jun 8. doi: 10.1002/ajmg.b.32328. PMID: 26059482, PMCID: PMC4638147 [Impact Factor: 3.4]
• Joel Eriksson, Dan Evans, Jian Shen, Priya Srikanth, Carrie Nielson, Marc Hochberg, Shannon McWeeney, Peggy Cawthon, Beth Wilmot, Joseph Zmuda, Greg Tranah, Daniel Mirel, Sashi Challa, Michael Mooney, Andrew Crenshaw, Magnus Karlsson, Dan Mellstršm, Liesbeth Vandenput, Eric Orwoll, Claes Ohlsson. Limited Clinical Utility of a Genetic Risk Score for the Prediction of Fracture Risk in Elderly Subjects. Journal of Bone Mineral Research, Jan 2015. PMID: 25043339, PMCID: PMC4281709 [Impact Factor: 6.1]
• Mooney MA, Nigg JT, McWeeney SK, Wilmot B. 'Pitfalls in the application of gene set analysis to genetics studies': a response. Trends Genet. 2014 Dec. 30(12):514-5. PMID: 25459302, PMCID: PMC4476633 [Impact Factor: 9.7]
• Michael A. Mooney, Shannon K. McWeeney, Joel Nigg, Beth Wilmot. Functional and Genomic Context in Pathway Analysis of GWAS Data. Trends in Genetics, 2014, September, 30(9):390-400. PMID: 25154796, PMCID: PMC4266582 [Impact Factor: 9.7]
• Robert Hitzemann, Daniel Bottomly, Ovidiu Iancu, Kari Buck, Beth Wilmot, Michael Mooney, Robert Searles, Christina Zheng, John Belknap, John Crabbe, and Shannon McWeeney. The Genetics of Gene Expression in Complex Mouse Crosses as a Tool to Study the Molecular Underpinnings of Behavior Traits. Mammalian Genome, 2013 Dec 31. PMID: 24374554, PMCID: PMC3916704 [Impact Factor: 2.4]
• Michael Mooney and Shannon McWeeney. "Data Integration and Reproducibility for High-Throughput Transcriptomics" in Brain Transcriptome, International Review of Neurobiology, Volume 116, 2014. PMID: 25172471 [Impact Factor: 1.9]
• Michael Mooney, Shannon McWeeney, Glenda Canderan, Rafick-Pierre Sekaly. A Systems Framework for Vaccine Design. Current Opinion in Immunology, 2013 Oct, 25(5):551-5. PMID: 24358511, PMCID: PMC3983719 [Impact Factor: 8.7]
• Michael Mooney, Shannon McWeeney, Rafick-Pierre Sekaly. Systems immunogenetics of vaccines. Seminars in Immunology, 2013 Apr, 25(2):124-9. PMID: 23886894, PMCID: PMC3815469 [Impact Factor: 5.9]
• Michael A. Mooney, Beth Wilmot, The Bipolar Genome Study, Shannon K. McWeeney. The GA and the GWAS: Using Genetic Algorithms to Search for Multi-locus Associations. IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 9, no. 3, pp. 899-910, May-June 2012. PMCID: PMC3748153 [Impact Factor: 1.4]
• Laderas T, Walter N, Mooney M, Vartanian K, Darakjian P, Buck K, Harrington C, Belknap J, Hitzemann R, McWeeney S. Computational Detection of Alternative Exon Usage. Frontiers in Neuroscience, 2011, 5:69. PMCID: PMC3097375 [Impact Factor: 3.6]
• Daniel Bottomly, Nicole A.R. Walter, Jessica Ezzell Hunter, Priscila Darakjian, Sunita Kawane, Kari J. Buck, Robert Searles, Michael Mooney, Shannon McWeeney and Robert Hitzemann. Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays. PLOS One, 2011 Mar 24, 6(3):e17820. PMCID: PMC3063777 [Impact Factor: 4.0]
• Walter NA, Bottomly D, Laderas T, Mooney MA, Darakjian P, Searles RP, Harrington CA, McWeeney SK, Hitzemann R, Buck KJ. High throughput sequencing in mice: a platform comparison identifies a preponderance of cryptic SNPs. BMC Genomics, 2009 Aug 17, 10:379. PMCID: PMC2743714 [Impact Factor: 4.4]

Presentations / Abstracts

• Beth Wilmot, Michael Mooney, Shannon McWeeney, Joel Nigg. Utilizing Genetic Architecture to Model Pathway Level Effects in Attention Deficit Hyperactivity Disorder. World Congress of Psychiatric Genetics, October 2014, Copenhagen, Denmark.
• Joel Eriksson, Dan Evans, Jian Shen, Priya Srikanth, Carrie Nielson, Marc Hochberg, Shannon McWeeney, Peggy Cawthon, Beth Wilmot, Joseph Zmuda, Greg Tranah, Daniel Mirel, Sashi Challa, Michael Mooney, Andrew Crenshaw, Magnus Karlsson, Dan Mellstršm, Liesbeth Vandenput, Eric Orwoll, Claes Ohlsson. Genetic Risk Scores for the Prediction of BMD, BMD Loss and Fracture Risk in Elderly Subjects. ASBMR, 2013, Baltimore, MD. (Poster)
• Michael Mooney The Bipolar Genome Study, Shannon McWeeney. Discovery of Polygenic Effects in Complex Diseases: An Opportunity for Machine Learning. Machine Learning in Systems Biology (MLSB13) workshop, ISMB/ECCB, July 19-20, 2013, Berlin, Germany. (Poster)
• Michael A. Mooney, Shannon K. McWeeney. The diversity of polygenic effects in complex diseases: an opportunity for machine learning. Research Week, Oregon Health & Science University. May 2013, Portland, OR. (Poster)
• Michael Mooney, Beth Wilmot, The Bipolar Genome Study, Shannon McWeeney. Epistasis Detection in Complex Traits: An Application to Bipolar Disorder. ISMB/ECCB, July 17-19, 2011, Vienna, Austria. (Oral Presentation - Late Breaking Research Session)
• Mooney MA, McWeeney SK. How Do We Transform Microarray Data into Clinically Relevant Information? Current Challenges and Opportunities in Cross-Platform Comparisons. 2008 AMIA Summit on Translational Bioinformatics. March 2008, San Francisco, CA. (Poster)
• Michael A. Mooney, Shannon K. McWeeney. Integrating Clinical and Genomic Data to Predict Leukemia Type. 2008 National Library of Medicine Training Conference. July 2008, NIH Campus. (Poster)
• Michael Mooney, Shannon McWeeney. Cross-Platform Comparisons of Microarray Data: Implications for the Role of Annotation. Illumina, Inc. Customer Seminar. November 2007, Vancouver, BC. (Invited Talk)
• Michael Mooney, Shannon McWeeney. Cross-Platform Comparisons of Microarray Data: Implications for the Role of Annotation. Illumina, Inc. Customer Seminar. November 2007, Seattle, WA. (Invited Talk)